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Adherence to isoniazid preventive chemotherapy: a prospective community based study
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  • Published on:
    Non-Adherence to TB treatment

    Dear Editor,

    Marais et al (1) reported on a prospective community based study into adherence of mono-chemotherapy with isoniazid in preventing tuberculosis in suburbs of Cape Town, South Africa. They studied children who were less than five years age and who had household contact with an adult pulmonary tuberculosis index case. The main evaluation was the children’s prescription collection at various intervals fr...

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    Conflict of Interest:
    None declared.
  • Published on:
    Directly observed therapy might improve compliance

    Dear Editor,

    Bearing in mind the risk of transmission of disease posed by infected adults, irrespective of whether or not they are smear positive for mycobacterium tuberculosis(1)(2), the poor compliance rate documented for children receiving preventive chemotherapy(3)is in urgent need of review and improvement. In this respect there might be a role for directly observed therapy(DOT)although this has been evaluated...

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    Conflict of Interest:
    None declared.