Responses

Download PDFPDF
Orphan diseases and orphan drugs: infant botulism and BIG-IV
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests

PLEASE NOTE:

  • Responses are moderated before posting and publication is at the absolute discretion of BMJ, however they are not peer-reviewed
  • Once published, you will not have the right to remove or edit your response. Removal or editing of responses is at BMJ's absolute discretion
  • If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patient's written consent to publication and send them to the editorial office before submitting your response [Patient consent forms]
  • By submitting this response you are agreeing to our full [Response terms and requirements]

Vertical Tabs

Other responses

Jump to comment:

  • Published on:
    Re: Orphan diseases and orphan drugs: infant botulism and BIG-IV

    Dear Editor,

    The Archivist’s mention in your journal (2006;91:611) of the recent success of Human Botulism Immune Globulin (BIG-IV) in the treatment of infant botulism noted that this orphan drug was available only in the United States, where it is licensed. BIG-IV demonstrated efficacy by shortening mean hospital stay by almost one month, from 5.7 weeks to 2.2 weeks. However, your contributor could not have...

    Show More
    Conflict of Interest:
    None declared.