Article Text

Download PDFPDF
No clinical evidence of hidden vCJD in UK children

Abstract

Between May 1997 and November 2004 this national prospective surveillance study identified 1007 children with “progressive intellectual and neurological deterioration” (PIND). In most cases specific diagnoses were made, but of 92 undiagnosed children with PIND 46 had died and only four underwent full necropsy. There was no clinical evidence of variant Creutzfeldt-Jakob disease (vCJD) in these undiagnosed cases, but without necropsy it is not possible to exclude vCJD completely.

  • PIND, progressive intellectual and neurological deterioration
  • vCJD, variant Creutzfeldt-Jakob disease
  • variant CJD
  • PIND
  • neurodegenerative diseases
  • necropsy

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles