Article Text

Download PDFPDF
Randomised controlled trial of combined paracetamol and ibuprofen for fever
  1. M D S Erlewyn-Lajeunesse1,
  2. K Coppens2,
  3. L P Hunt1,
  4. P J Chinnick2,
  5. P Davies2,
  6. I M Higginson2,
  7. J R Benger3
  1. 1Clinical Sciences at South Bristol, Faculty of Medicine, University of Bristol, UK
  2. 2Children’s Emergency Department, Bristol Royal Hospital for Children, Bristol, UK
  3. 3Faculty of Health and Social Care, University of the West of England, Bristol, UK
  1. Correspondence to:
    Dr M Erlewyn-Lajeunesse
    Institute of Child Life & Health, UBHT Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK; Mich.Lajeunesse{at}


A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.

  • acetaminophen
  • preschool
  • fever
  • ibuprofen

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.