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Osteomyelitis of the humerus complicating BCG vaccination
  1. S Segal1,
  2. A J Pollard1,
  3. C Watts2,
  4. A Wainwright3,
  5. A Lalvani4,
  6. J Connell5
  1. 1Dept of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK
  2. 2Dept of Radiology, University of Oxford, John Radcliffe Hospital
  3. 3Dept of Orthopaedics, Nuffield Orthopaedic Centre, Oxford, UK
  4. 4Dept of Medicine, University of Oxford, John Radcliffe Hospital
  5. 5Dept of Paediatrics, Wexham Park Hospital, Slough, UK
  1. Correspondence to:
    Dr S Segal
    Department of Paediatrics, University of Oxford, Level 4, John Radcliffe Hospital, Oxford OX3 9DU, UK; shelley.segal{at}

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An 18 month old boy presented with reluctance to move his left arm after a fall. He had received bacille Calmette-Guérin (BCG) vaccination six months prior to presentation. Radiological examination of the humerus showed a proximal pathological fracture and a number of lytic lesions. Magnetic resonance imaging showed an aggressive lesion within the proximal metaphysis with cortical disruption.

A bone biopsy showed …

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  • Competing interests: none declared