Article Text

Download PDFPDF
Developmental origins of health and disease
  1. R L Boon

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Edited by Peter Gluckman, Mark Hanson. Published by Cambridge University Press, Cambridge, 2006, £85.00, pp 519. ISBN 0-521-84743-5

Embedded Image

Congratulations to the desert locust—for its first appearance in Archives. What, you may well be wondering, warrants this illustrious debut. Well, Schistocerca gregaria, as it is known to its close friends, is one of several examples from comparative biology that are used to illustrate the concept of development plasticity. At the larval stage, this insect is able to “choose” which phenotype to express—if food in the vicinity is plentiful, then it will develop a non-migratory wing pattern; if scarce, then its wings will be more geared towards flying in search of food. Animal studies have now firmly established that there are windows of opportunity during development in which environmental factors can affect which phenotype is expressed. This is one …

View Full Text