Statistics from Altmetric.com
Fetal urine production begins towards the end of the first trimester. Angiotensin converting enzyme (ACE) inhibitors are thought to produce a fetopathy by inhibiting fetal urine production and therefore only do so when taken in the second and third trimesters: the drugs have been considered safe in the first trimester. Features of the fetopathy include renal dysplasia and renal failure, oligohydramnios, hypoplastic calvaria, and intrauterine growth retardation. [Perhaps strangely, if the condition is secondary to fetal anuria or oliguria, they do not seem to …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.