Article Text

PDF

MRSA at an English children’s hospital from 1998 to 2003
  1. A Adedeji,
  2. J W Gray
  1. Birmingham Children’s Hospital, UK
  1. Correspondence to:
    Dr A Adedeji
    Department of Microbiology, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham B4 6NH, UK; adekolaahotmail.com

Abstract

Aims: To investigate the epidemiological and clinical aspects of MRSA among inpatients and outpatients presenting to hospital.

Methods: Analysis of demographic, epidemiological, and clinical data collected on 385 children first identified as having MRSA between January 1998 and December 2003 in a 250 bed English children’s hospital.

Results: There were 267 inpatients and 118 outpatients. The number of new cases of MRSA declined from 72 in 1998 to 52 in 2003, whereas hospital activity increased. Ninety nine (37.1%) inpatients acquired MRSA outside the hospital; a further 90 occurred among 31 clusters of cases. One hundred and seventy eight (66.7%) inpatients were aged <2 years; cardiac services and paediatric & neonatal surgery accounted for 59.6% of cases. Dermatology and A&E accounted for 51.7% of outpatients; 73.8% of outpatients had recently previously attended the hospital. A total of 13.9% of inpatients with MRSA developed bacteraemia; MRSA accounted for 15% of Staphylococcus aureus bacteraemias. The risk of MRSA bacteraemia in colonised patients, and the proportion of S aureus bacteraemias that were MRSA, varied between specialties. Intravascular devices were the most common source of MRSA bacteraemia (63.4% of cases). The mortality rate was 7.3%.

Conclusions: Enhanced surveillance of MRSA can identify at-risk patient groups, thus facilitating targeting of control measures. The absence of a link between numbers of cases of acquisition of MRSA and bacteraemia suggests that the rise in MRSA bacteraemia may not solely reflect an increase in MRSA prevalence in children in the UK. The need for larger epidemiological studies is emphasised.

  • MRSA, methicillin resistant Staphylococcus aureus
  • MSSA, methicillin sensitive Staphylococcus aureus
  • PICU, paediatric intensive care unit
  • MRSA bacteraemia
  • epidemiology
  • prevalence
  • control measures

Statistics from Altmetric.com

Footnotes

  • Competing interests: none

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Atoms
    Howard Bauchner