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Biomarkers in paediatric research and practice
  1. B P Lanphear1,
  2. C F Bearer2
  1. 1Cincinnati Children’s Environmental Health Center, Cincinnati Children’s Hospital Medical Center, Departments of Pediatrics and of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA
  2. 2Departments of Pediatrics and of Neurosciences, Mary Ann Swetland Center for Environmental Health, Case Western Reserve University School of Medicine, Rainbow Babies & Children’s Hospital, Cleveland, Ohio, USA
  1. Correspondence to:
    Dr B P Lanphear
    Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229-3039, USA;


Children’s health is, to a large extent, a function of their environment. Infectious agents remain the leading cause of death and disability in the world. In contrast, many of the new morbidities—asthma, intellectual impairments, behavioural problems, and cancer—are linked with industrial pollutants or other environmental influences. Our understanding of the risk factors for many diseases is incomplete, but it is widely recognised that disability and death result largely from interactions of environmental factors, broadly defined, and host susceptibility.1–3

  • biomarker
  • environmental health
  • epidemiology
  • toxins

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  • Funding: funded in part by NIEHS and US EPA (PO1-ES11261)

  • Competing interests: none declared

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