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Successful tacrolimus (FK506) therapy in a child with pyoderma gangrenosum
  1. J M Deckers-Kocken,
  2. S G M A Pasmans
  1. Wilhelmina Children’s Hospital, University Medical Center Utrecht, Huispost KE01.147.0, PO Box 85090, 3508 AB Utrecht, Netherlands;

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    A 12.5 year old boy with colitis ulcerosa, in remission for a year after colectomy, presented with an ulcus on the right lower leg. Pyoderma gangrenosum as extra-intestinal manifestation of the colitis was diagnosed. Topical tacrolimus (protopic = FK506 0.1%) twice a day was started, resulting in an initial improvement of the ulcus. As the ulcus relapsed and started to …

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    • Competing interests: the authors have no financial binding with any pharmaceutical company

      Parental consent was obtained for publication of figures