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Bisphosphonate treatment of bone disease
  1. N J Shaw1,
  2. N J Bishop2
  1. 1Department of Endocrinology, Birmingham Children’s Hospital, UK
  2. 2Academic Unit of Child Health, Sheffield Children’s Hospital, University of Sheffield, UK
  1. Correspondence to:
    Dr N J Shaw
    Dept of Endocrinology, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham B4 6NH, UK;


In 1997 a review article on bisphosphonates in this journal identified 24 published articles relating to children at that time.1 Since then there has been a considerable increase in their use in clinical paediatric practice and research with there being nearly a further one hundred articles published at the time of writing.

  • bisphosphonates
  • treatment

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  • Competing interests: NJS and NJB have received funding from Novartis and the Arthritism & Rheumatism Council for studies of bisphosphonates in osteogenesis imperfecta. NJB has acted as an independent consultant for Proctor & Gamble.