Effect of Gaviscon Infant on gastro-oesophageal reflux in infants assessed by combined intraluminal impedance/pH
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  • Published on:
    Gaviscon Infant® is effective symptomatically in infant reflux-associated symptoms

    Dear Editor

    In response to the comments of Paisal (1), regarding our study on the influence of Gaviscon Infant® on gastro-oesophageal reflux in infants studied by the new physiologically appropriate modality of combined intraluminal oesophageal pH/impedance (2), we would like to make the following points.

    Commenting on the study design he points to two studies which found benefit of Gaviscon. What he...

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    Conflict of Interest:
    None declared.
  • Published on:
    Gaviscon on gastro-oesophageal reflux in infants: A poorly effective treatment?
    • Francesco Cresi, Paediatric Specialist
    • Other Contributors:
      • Francesco Savino, Cristina Marinaccio, Leandra Silvestro

    Dear Editor,

    We read with interest the recent article by Del Buono et al. evaluating the effect of sodium and magnesium alginate (Gaviscon) on gastro-oesophageal reflux (GER) in infants [1]. It provides an objective assessment of the effects of a drug widely used in the treatment of paediatric GER by means of a double-blind drug vs placebo trial, in which the effects of each treatment were evaluated by means of...

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    Conflict of Interest:
    None declared.
  • Published on:
    Absence of wash-out period between Gaviscon and placebo may be responsible for anomalous findings

    Dear Editor,

    Oesophageal pH monitoring has been used to monitor gastro-oesophageal reflux (GOR). However, Buono et al. point out that this method will not record instances of 'neutral-reflux' after a feed (1). They say that multiple intraluminal impedance measurement is a more appropriate way to assess GOR. Using the technique they have found that Gaviscon does not reduce reflux. The number and height of reflux with Gav...

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    Conflict of Interest:
    None declared.