Article Text
LETTER
Hib IgG persistence following early booster dose
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A diphtheria/tetanus/acellular pertussis–Haemophilus influenzae type b vaccine (DTaP–Hib), introduced to the UK in 1999, was associated with poor primary Hib responses1 and a resurgence of Hib disease in the population.2 Consequently, in 2003, the UK Department of Health undertook a campaign to immunise children aged 6 months–4 years with an additional dose of Hib. We have previously shown a significant rise in Hib titres following an additional Hib dose, given before one year, in infants with very low primary responses.3 Here we describe how that response persists. …
Footnotes
Competing interests: none declared