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Clinical assessment of neonatal hyperbilirubinaemia
  1. A Kanjilal1,
  2. P L Prasad1
  1. 1Military Hospital Allahabad, Allahabad 211001, India; kanjilal1@sancharnet.in

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The study by Keren and colleagues1 is a retrospective study, using infants in whom pre- and post-discharge TSB has been carried out, hence causing an inherent bias towards the same group.

The data for clinical risk have been collected from documents such as admission, intrapartum, and discharge forms. This retrospective collection can result in missing or ambiguous data, as has been accepted by the authors. Ideally, a study should be prospective using both methods on all neonates in a study group, and then the sensitivity and specificity (that is, false positives and false negatives) should be compared using actual data on follow up.

The clinical risk factor score includes factors that are interrelated such as vacuum and cephalhematoma. In cases where the cephalhematoma is caused by the use of vacuum the neonate gets a double rating. Obviously, authors have not found clinical risk factors more specific than pre-discharge TSB.

Contrary to this study, the AAP guidelines promote and support breast feeding and state that effective breast feeding can reduce substantially the risk for hyperbilirubinaemia.2 It is known that inadequate feeds increase …

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