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In a preterm infant, does blood transfusion increase the risk of necrotizing enterocolitis?
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  • Published on:
    Almost certainly a straw that could break the camel's back.

    Dear Editor,

    Andrew Short et al. draw attention to Marik and Sibbld's observation that, "change in intraluminal [in reality intramucosal or intramural :pHi) as distinct from intraluminal] pH, as measured by gastric tonometry, was more marked if the red cells had been stored for more than 15 days". Their study showed that if there was a benefical effect on tissue oxugentation it was confined to fresh blood. More im...

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    Conflict of Interest:
    None declared.
  • Published on:
    Necrotising Enterocolitis following blood transfusion
    • Andrew Short, Consultant Paediatrician
    • Other Contributors:
      • Andrew Gallagher, Munir Ahmed

    Dear Editor

    We read with interest the article questioning whether blood transfusion increases the risk of necrotising enterocolitis (NEC). We, like many paediatricians, are convinced of an association and would like to add to the anecdotal evidence so that in future greater thought will be given to the role of "top-up" transfusions in preterm infants.

    Case 1

    A male infant was born by caesarean...

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    Conflict of Interest:
    None declared.