G205 THIRD TRIMESTER ULTRASOUND SCAN: BETTER PREDICTOR OF RENAL TRACT ANOMALIES?

H. Narchi. Paediatric Department, Sandwell General Hospital, West Bromwich B71 4HJ, UK

Aim: To compare the incidence of renal tract anomalies diagnosed following foetal renal dilatation detected incidentally in late pregnancy with that detected during the recommended 20 week scan.

Material and Methods: A routine 20 week scan was carried out on a cohort of 4992 pregnant women. Fetuses with renal dilatation were rescanned at 28 weeks and those with persistent dilatation constituted group A. Group B consisted of fetuses with renal tract dilatation diagnosed on incidental third trimester scan. Postnatal investigations were performed according to a well defined protocol and the incidence of diagnosed renal tract anomalies detected was compared between both groups.

Results: In group A (44 infants) there was one infant with vesico-ureteric reflux (VUR) and another with a unilateral pelvi-ureteric junction obstruction. In group B (12 infants, of whom eight had an earlier normal scan at 20 weeks), two infants had VUR, one had renal dysplasia, and one had posterior urethral valve with absent right kidney. The incidence rate for VUR was 16.16 times higher (95% CI 0.80 to 953.9) when dilatation was diagnosed in the third trimester compared with the 20 week scan.

Conclusion: The 20 week scan may not be the best time to detect renal tract abnormalities and may be falsely reassuring. During any scan in the third trimester, even with a prior normal 20 week scan, renal tract dilatation should be looked for as its presence at that stage is more likely to be associated with renal tract anomalies.

G206 INTRAUTERINE PROGRAMMING OF URINARY CALCIUM AND MAGNESIUM EXCRETION IN CHILDREN BORN TO MOTHERS WITH INSULIN DEPENDENT DIABETES MELLITUS

M. Z. Mughal, J. Eelloo, S. Sibartie, S. A. Roberts, M. Maresh, C. P. Sibley, J. E. Adams. Central Manchester and Manchester Children’s Hospitals and the University of Manchester, Manchester, UK

Background: Offspring of diabetic rats have reduced urinary calcium and magnesium excretion …