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G58 ANTIBIOTICS IN SEVERE RSV POSITIVE BRONCHIOLITIS
S. Harigopal1, K. Thorburn1, N. Taylor2, H. K. F. van Saene2. 1Department of Paediatric Intensive Care; 2Deparment of Microbiology, Royal Liverpool Children’s Hospital–Alder Hey, Liverpool, UK
Introduction: The use of antibiotics in severe bronchiolitis has long been debated. There are no studies to date on the incidence of bacterial co-infection in severe bronchiolitis.
Objectives: To determine the incidence of bacterial co-infection in RSV + bronchiolitis in a tertiary paediatric intensive care unit and to study the impact of co-infection in this patient group.
Methods: Prospective microbiological analysis of endotracheal aspirates on all RSV + bronchiolitis patients on admission to the PICU.
Results: A total of 44 patients, all ventilated, were studied. Median age 2.0 months (IQR: 1.1–5.1). 24 received antibiotics before admission. 17 (39%) cultured bacteria from the endotracheal aspirate on admission to the paediatric intensive care unit: 7 (16%) infected, 10 (23%) colonised. 10/17 (59%) had comorbidities (congenital heart or chronic lung disease, immunodeficiencies, abnormality of large airways) as compared to 11/27 (37%) in RSV only group. There were 2 deaths, 1 in the co-infection group (pertussis, requiring ECMO) and 1 in the RSV only group (oncology patient).
Conclusions: Prior antibiotics may have influenced the colonisation group. The incidence of bacterial co-infection in patients admitted to the PICU with severe RSV bronchiolitis was between 16% and 39%. This supports the use of prophylactic antibiotics in this cohort of severe RSV disease.
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G59 A CHILD’S ADMISSION TO HOSPITAL: A QUALITATIVE STUDY EXAMINING EXPERIENCES OF CHILDREN AND PARENTS
A. Diaz-Caneja, J. Gledhill, T. Weaver, S. Nadel, E. Garralda. St Mary’s Hospital, London
Aims: To explore experiences of parents and children during admission to hospital either paediatric intensive care unit (PICU) or general paediatric ward (GPW); to increase understanding of nature of stress of …