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Hypoxaemia in sickle cell disease

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Hypoxaemia, generalised or local, causes sickling of red cells in people with sickle cell disease and there is evidence that nocturnal hypoxaemia may be a cause of central nervous system complications and vaso-occlusive crises. Researchers in Philadelphia (OpenUrlCrossRefPubMedWeb of Science) have shown that children with severe sickle cell disease may be hypoxaemic both …

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