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The need for caution in considering the diagnostic utility of antibasal ganglia antibodies in movement disorders
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  • Published on:
    Caution in considering the diagnostic utility of antibasal ganglia antibodies
    • Harvey S. Singer, Haller Professor of Pediatric Neurology
    • Other Contributors:
      • John J. Hong, Christopher Rippel, Dustin Yoon, Phillip Williams, Carlos Pardo

    Dear Editor,

    The authors appreciate the comments of Dr Giovannoni and fully recognize the ongoing efforts of the London group in evaluating antibasal ganglia antibodies (ABGA) in poststreptococcal movement conditions. Nevertheless, readers must recognize that there are significant discrepancies between results reported in the article by Church et al., [1] and other investigators [2,3].

    In or...

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    Conflict of Interest:
    None declared.
  • Published on:
    Anti-basal ganglia antibodies in movement disorders

    Dear Editor,

    In their commentary in response to our study on the diagnostic utility of anti-basal ganglia antibodies (ABGA) in post-streptococcal movement disorders, Singer and colleagues [1] raise certain points and present laboratory data which require a considered response.

    The band at ~55 kDa appears to be in saturation and the number of bands detected raises the issue of non-specific or low affini...

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    Conflict of Interest:
    None declared.