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The significance of a high plasma ammonia value

Abstract

At a tertiary referral centre, just over 50% of patients with plasma ammonia values over 200 μmol/l had inborn errors of metabolism. To distinguish artefactual high values from those requiring treatment, the measurement should be repeated immediately if the result is above 200 μmol/l and at lower concentrations if the patient is encephalopathic.

  • ammonia
  • hyperammonaemia
  • organic acidaemia
  • urea cycle

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