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Aspirin, Reye syndrome, Kawasaki disease, and allergies; a reconsideration of the links
  1. H P van Bever1,
  2. S C Quek1,
  3. T Lim2
  1. 1Department of Paediatrics, National University of Singapore
  2. 2Department of Paediatrics, National University Hospital, Singapore
  1. Correspondence to:
    Prof. H P van Bever
    Department of Paediatrics, National University Hospital, Singapore, 5 Lower Kent Ridge Road, Singapore 119074; paevbhpsnus.edu.sg

https://doi.org/10.1136/adc.2004.055681

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    Reye syndrome is very uncommon in Kawasaki disease patients despite the widespread use of aspirin. It is time to rethink the link between aspirin and Reye syndrome in the light of the rising prevalence of allergies for which the declining use of aspirin may be contributory.

    The use of aspirin (ASA) has declined dramatically since the 1980s following reports linking its use to Reye syndrome. …

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