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Cause and effect?
  1. I Rodd
  1. Royal Hampshire County Hospital, Winchester SO22 5DG, UK; ian.rodd{at}

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I read Feltblower and colleagues’ article1 with great interest, having for some time wondered whether there might be an epidemiological association between childhood leukaemia and diabetes. The observations that the authors make regarding regional distribution of disease within a country certainly warrant further investigation.

Coincidentally, Mohn and colleagues2 have recently shown clinically significant impairment of pancreatic beta cell function in children who have been treated for acute lymphoblastic leukaemia (ALL). Although the numbers will certainly be small, is it possible that some of the observed correlation between these two conditions could stem from “iatrogenic” diabetes?