The concentrations of maternal anti-RSV IgG antibodies were followed in 49 healthy newborns over the first six months of life.
At birth, 41 mothers (83%) tested positive for anti-RSV IgG and all of their babies carried maternal anti-RSV IgG. Anti-RSV IgG positivity dropped to 73% at 1 month, 6% at 3 months, and 2% at 6 months.
Between 3 and 6 months, 8% did acquire RSV infection, half of them as acute bronchiolitis and half as non-specific respiratory infection. All of the patients who acquired clinical RSV disease had an antibody concentration of <20 RU/ml which may be the cut off value for protection.
- respiratory syncytial virus
- maternal antibodies
- AB, acute bronchiolitis
- RSV, respiratory syncytial virus
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This investigation was funded by the Uludag University Research Fund
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