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Community child health, public health, and epidemiology
Soy formula complicates management of congenital hypothyroidism
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  • Published on: 15 March 2004
    Soy fibers and levothyroxine bioavailability
    • Yair Liel, Endocrinologist
    • Other Contributors:
      • Soroka University Medical Center, Beer-Sheva, Israel

    Dear Editor

    I have read with interest the article by Conard et al. regarding the adverse effect of soy formula on levothyroxine (lT4) treatment in congenital hypothyroid infants. We have previously shown that adults consuming low- calorie bread, rich in soy fibers, require considerably higher lT4 doses to achieve an euthyroid state.[1] It should also be noted, that due to the entero-hepatic cycle of thyro...

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    Conflict of Interest:
    None declared.