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Mesial temporal sclerosis and temporal lobe epilepsy

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Mesial temporal sclerosis is the most common lesion found in adults with temporal lobe epilepsy. For many years it has been held that these lesions may be related to complicated febrile convulsions in childhood but the association is based on retrospective data and a cause-and-effect relationship has not been proved. A magnetic resonance imaging (MRI) follow up study of children after febrile convulsions (

) has shown no evidence of mesial temporal sclerosis.

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