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Treatment of meningococcal infection
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  • Published on:
    Authors' response
    • Steven B Welch, Clinical Research Fellow in Paediatric Infectious Diseases
    • Other Contributors:
      • Simon Nadel

    Dear Editor

    We are grateful for the opportunity to respond to the important point raised by Professor Choonara[1] regarding the optimal duration of antibiotic treatment in children with meningococcal infection.

    It is undoubtedly true that meningococci are rapidly killed by appropriate antibiotics, and it is probably true that, at least in uncomplicated cases, courses of less than seven days’ duration may be ad...

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    Conflict of Interest:
    None declared.
  • Published on:
    Treatment of Meningococcal Infection

    Dear Editor

    It is disappointing to see that Welch and Nadel [1] recommend seven days treatment with antibiotics for children with uncomplicated meningococcal infection. An evidence-based approach would support the use of four days intravenous therapy. There have been two clinical trials that have evaluated the duration of therapy. A prospective study of four days treatment with intravenous benzylpenicillin for 50...

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    Conflict of Interest:
    None declared.