Article Text

Download PDFPDF

Pathophysiology of meningococcal meningitis and septicaemia
Free
  1. N Pathan,
  2. S N Faust,
  3. M Levin
  1. Imperial College of Science, Technology & Medicine, London, UK
  1. Correspondence to:
    Prof. M Levin, Department of Paediatrics, Faculty of Medicine, Imperial College of Science, Technology & Medicine, Norfolk Place, London W2 1PG, UK;
    m.levin{at}ic.ac.uk

Abstract

Neisseria meningitidis is remarkable for the diversity of interactions that the bacterium has with the human host, ranging from asymptomatic nasopharyngeal colonisation affecting virtually all members of the population; through focal infections of the meninges, joints, or eye; to the devastating and often fatal syndrome of meningococcal septic shock and purpura fulminans.

  • meningitis
  • meningococcaemia
  • septic shock
  • CSF, cerebrospinal fluid
  • IL, interleukin
  • NCAM, neural cell adhesion molecule
  • PAI, plasminogen activator inhibitor
  • TFPI, tissue factor pathway inhibitor
  • TNF, tumour necrosis factor
View Full Text

Statistics from Altmetric.com

Footnotes

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.