Neisseria meningitidis is remarkable for the diversity of interactions that the bacterium has with the human host, ranging from asymptomatic nasopharyngeal colonisation affecting virtually all members of the population; through focal infections of the meninges, joints, or eye; to the devastating and often fatal syndrome of meningococcal septic shock and purpura fulminans.
- septic shock
- CSF, cerebrospinal fluid
- IL, interleukin
- NCAM, neural cell adhesion molecule
- PAI, plasminogen activator inhibitor
- TFPI, tissue factor pathway inhibitor
- TNF, tumour necrosis factor
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