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Islet transplant: an option for childhood diabetes?
  1. E Hathout1,
  2. J Lakey2,
  3. J Shapiro3
  1. 1Director, Pediatric Diabetes Center and Chief, Division of Endocrinology and Diabetes, Loma Linda University Children’s Hospital, Loma Linda, USA
  2. 2Director, Clinical Islet Isolation Laboratory, University of Alberta
  3. 3Director, Clinical Islet Transplant Program and Clinical Research Chair in Transplantation, University of Alberta
  1. Correspondence to:
    Dr J Shapiro, Director, Clinical Islet Transplant Program, Clinical Research Chair in Transplantation (CIHR/Wyeth Canada), Roberts Centre, University of Alberta, 2000 College Plaza, 8215 112 St, Edmonton AB, Canada T6G 2C8;
    amjs{at}islet.ca

Abstract

Careful assessment of the safety and efficacy of islet transplantation should guide the selection process of a small number of children with type 1 diabetes who may be eligible for the procedure—some of whom are already receiving immunosuppression because of a previous transplant, others who are scheduled to receive de novo islet alone transplantation because of a life threatening risk of hypoglycemia. The outcomes of these initial investigations are predicted to shape the future boundaries of islet transplantation, diabetes, and transplantation.

  • islet transplant
  • diabetes

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