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In Australia (
) a 10 year old boy with moderate intellectual impairment and severe problems with impulse control was found to have a pericentric inversion of chromosome 3 (46N inv (3) (p14q21). The same inversion was found in 10 other family members. The inversion was associated with intellectual impairment and impulsive behaviour. One child had been treated for attention deficit hyperactivity disorder.
Infants of mothers with gestational diabetes may be at increased risk of the oculo-auriculo-vertebral sequence of anomalies (OAVS). Data from a Spanish birth defects registry showed a 2.3-fold increase in risk in infants of mothers with gestational diabetes but no increased risk for the infants of mothers with diabetes diagnosed before pregnancy. In Los Angeles (
) 30 infants of diabetic mothers had dysplastic ears or features of OAVS. Half of these had hemifacial microsomia, 14 had hearing loss, 11 had heart defects, 10 had facial palsy, and 10 had vertebral anomalies. Other associated defects included renal anomalies, limb defects, Di George sequence, and imperforate anus.
Lymphocytic myocarditis occurs more often in children than in adults. Viruses known to cause it include enterovirus, adenovirus, mumps virus, influenza virus, and human immunodeficiency virus. Parvovirus myocarditis has been described in only a few reports. In Stockholm (
) an 11-month old girl presented with …
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