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Another case of HBV associated membranous glomerulonephritis resolving on lamivudine
  1. G Filler,
  2. J Feber,
  3. G Weiler,
  4. N Le Saux
  1. Children’s Hospital of Eastern Ontario, Department of Paediatrics, 401 Smyth Road, Ottawa, ON, K2H 7M9, Canada
  1. Correspondence to:
    Prof. G Filler, Professor of Paediatrics, Head, Division of Nephrology, Children’s Hospital of Eastern Ontario, University of Ottawa, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada;
    filler{at}cheo.on.ca

https://doi.org/10.1136/adc.88.5.460

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    Connor and colleagues1 (see 446) report rapid resolution of a hepatitis B associated membranous glomerulopathy and nephrotic syndrome after two months of oral lamivudine. We would like to add our experience with lamivudine in a similar case.

    A 5 year old female of Vietnamese origin presented with a two week history of periorbital swelling and weight gain. She had 3 plus protein, 10–20 dysmorphic red blood cells, and red blood cell casts in her urine. Serum albumin was low at 19 g/l, cholesterol was 9.8 mmol/l, and serum complement C3 and C4 were reduced (0.61 g/l and <0.1 g/l, respectively). She was hepatitis B surface antigen positive and hepatitis B surface antibody negative. …

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