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Increasing antibiotic resistance among urinary tract isolates
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  • Published on:
    Antibiotic resistance in urinary tract isolates and risk of renal scarring.
    • Michael Eisenhut, Paediatric Registrar
    • Other Contributors:
      • Faye El Masri, Caroline A. Jones

    Dear Editor

    Lakhani and Gransden [1] stated in their article that in urinary tract infection the initial use of an antibiotic the urinary tract isolate is resistant to will through a delay in effective treatment lead to an increased risk of renal scarring. The authors concluded that nitrofurantoin should replace trimethoprim as the first line antibiotic for treatment of urinary tract infection (UTI) in childhood beca...

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    Conflict of Interest:
    None declared.
  • Published on:
    Clinically relevant data needed to inform prescribing decisions

    Dear Editor

    Ladhani and Gransden are right to encourage other units to review local data on antibiotic resistance among urinary tract isolates. There is not adequate evidence to suggest one antibiotic is superior to others in presumptive therapy of urinary tract infection (UTI).[1] Local antibiotic susceptibility patterns should thus help make the antibiotic choice. However I have two major concerns about their con...

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    Conflict of Interest:
    None declared.