You are here

Article Text

Article menu
Download PDFPDF
Letter
Ketoacid levels may alter osmotonicity in diabetic ketoacidosis and precipitate cerebral edema
  1. J M Puliyel,
  2. V Bhambhani
  1. St Stephens Hospital, Tis Hazari, Delhi, India
  1. Correspondence to Dr Puliyel; puliyel{at}vsnl.com

https://doi.org/10.1136/adc.88.4.366-a

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Inward and Chambers1 have called for a rethink of the management of diabetic ketoacidosis. In their article they quote a study by Grove L M and colleagues2 suggesting that pediatricians overestimated the quantum of dehydration in DKA. Over correction of dehydration is implicated in precipitating cerebral oedema. On the face of it, it seems implausible that pediatricians who are so adapt at estimating dehydration in the context of gastroenteritis, diarrhea, and vomiting should err in estimating the dehydration in DKA, unless the dehydration of DKA has special features. Hypertonicity may be that special feature. We hypothesize that …

    View Full Text