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Mycoplasma pneumoniae associated organising pneumonia in a 10 year old boy
  1. O Wachowski1,
  2. S Demirakça1,
  3. K-M Müller2,
  4. W Scheurlen1
  1. 1Department of Pediatrics, University of Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany
  2. 2Department of Pathology, Bergmannsheil, University of Bochum, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany
  1. Correspondence to:
    Prof. Dr Wolfram Scheurlen, Children’s Hospital, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany;
    w.scheurlen{at}kikli.ma.uni-heidelberg.de

Abstract

We describe a 10 year old boy with organising pneumonia associated with acute Mycoplasma pneumoniae infection. The diagnosis of organising pneumonia was made by open lung biopsy and the M pneumoniae infection was proven serologically. Antibiotic and long term corticosteroid treatment resulted in steadily improving pulmonary function monitored by spirometry. The introduction of anti-inflammatory treatment with NSAIDs/immunosuppressive agents in order to spare steroids was well tolerated and resulted in further improvement of the pulmonary function. To our knowledge this is the first documented case of Mycoplasma pneumoniae associated organising pneumonia to be reported in a child.

  • organizing pneumonia
  • Mycoplasma pneumoniae
  • spirometry
  • autoimmunity
  • NSAID
  • immunomodulatory drug
  • BOOP, bronchiolitis obliterans organising pneumonia
  • COP, cryptogenic organising pneumonia
  • FEV1, forced expiratory volume in 1 second
  • FVC, forced vital capacity
  • HR-CT, high-resolution computer tomography
  • NSAID, non-steroidal anti-inflammatory drug
  • ssDNA single strand DNA

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