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Importance of timing of risk factors for cerebral oedema during therapy for diabetic ketoacidosis
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  • Published on:
    Response to the letter of Dr Oudesluys-Murphy

    Dear Editor

    We thank Dr Oudesluys-Murphy for her letter in response to our article. In essence, two points were raised.

    I. Can one estimate the deficits of Na+ and water if one applies the formula proposed by Katz [1]]?

    This calculation makes the presumption that one can predict the change in plasma sodium concentration (PNa) when water is drawn out of cells by hyperglycaemia. This assumpti...

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    Conflict of Interest:
    None declared.
  • Published on:
    Changes in serum sodium levels during treatment of hyperglycaemia

    Dear Editor

    We read the paper by Carlotti et al. [1] with great interest.

    They state that fluid and electrolyte management might contribute to the development of cerebral oedema partly because clinicians do not have good data to predict the extent of deficits of sodium, potassium and water. However, there is a simple rule of thumb, formulated by Katz, which may help to calculate these deficits and pr...

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    Conflict of Interest:
    None declared.