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Acute paediatrics
An unusual presentation of perinatally transmitted hepatitis C
  1. P Mohan1,
  2. R S Chandra1,
  3. D E Kleiner2,
  4. N L C Luban1
  1. 1Departments of Pediatric Gastroenterology and Nutrition, Pathology and Laboratory Medicine, Children’s National Medical Center, George Washington University School of Medicine, Washington DC, USA
  2. 2Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
  1. Correspondence to:
    Dr Mohan, Department of Gastroenterology and Nutrition, Children’s National Medical Center, 111 Michigan Avenue, NW Washington, DC 20001, USA;
    pmohan{at}cnmc.org

Abstract

A unique presentation of perinatally acquired hepatitis C (HCV) with acute jaundice and chronic aggressive liver disease in a previously asymptomatic preadolescent is described. The difficulties in establishing the diagnosis and the importance of confirmatory testing for HCV in cryptogenic liver disease are discussed.

  • hepatitis C
  • perinatal transmission
  • liver biopsy
  • seronegativity

https://doi.org/10.1136/adc.88.2.160

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