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Acute disseminated encephalomyelitis: recognition in the hands of general paediatricians
  1. M Stonehouse1,
  2. G Gupte2,
  3. E Wassmer1,
  4. W P Whitehouse3
  1. 1Department of Paediatric Neurology, Birmingham Children’s Hospital, Birmingham, UK
  2. 2Department of General Paediatrics, Walsgrave Hospital, Coventry, UK
  3. 3Academic Division of Child Health, University of Nottingham, Nottingham, UK
  1. Correspondence to:
    Dr W P Whitehouse, Senior Lecturer in Paediatric Neurology, Academic Division of Child Health, E Floor East Block, Queen’s Medical Centre, Nottingham NG7 2UH, UK;


Acute disseminated encephalomyelitis will often present to the general paediatrician as an acute polysymptomatic encephalopathy, and initially the diagnosis may not be clear. A brain MRI scan is essential in establishing the diagnosis and so enabling appropriate advice and treatment to be given. Multicentre clinical audit of outcome and controlled therapeutic trials are needed to secure an evidence base for current practice.

  • ADEM
  • demyelination
  • multiple sclerosis
  • MRI
  • diagnosis
  • ADEM, acute disseminated encephalomyelitis
  • CSF, cerebrospinal fluid
  • CT, computed tomography
  • MRI, magnetic resonance imaging
  • MS, multiple sclerosis

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