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Osteogenesis imperfecta and intravenous pamidronate
  1. I Banerjee1,
  2. G J Shortland1,
  3. W D Evans1,
  4. J W Gregory2
  1. 1Department of Child Health, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK; ibanerjee@freeuk.com
  2. 2University of Wales, College of Medicine, Heath Park, Cardiff CF14 4XN, UK

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Osteogenesis imperfecta (OI) is a chronic, disabling condition in which treatment with cyclical intravenous treatment with pamidronate can be useful for symptom relief,1 despite questions about long term safety.2 A recent study3 in this journal showed a decrease in bone turnover and gradual increase in bone density measurements without significant side effects, following such treatment in children affected with OI.

We wish to report our own experience …

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