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Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom
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  • Published on:
    Adrenal axis suppression in children with long term inhaled corticosteroids treatment

    Dear Editor

    With reference to the recent article of Todd et al.[1] about adrenal crisis associated with inhaled corticosteroids, we report two cases of adrenal axis suppression in children with this treatment.

    The first one[2] is a 18 months boy, who had been diagnosed of bronchial hyperresponsiveness, and was in treatment with high dose of inhaled fluticasone (FP) (1000 mcg/day) since he was 9 mo...

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    Conflict of Interest:
    None declared.
  • Published on:
    Use of inhaled corticoseroids in children

    Dear Editor

    I read with interest the article Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom by Todd et al. and the accompanying editorial in the December issue of Archives of Disease in Childhood.

    In the reported cases, the children had been administered substantially (up to 5 times) higher than the Glaxo SmithKline Core Data Sheet recommended Flixotide d...

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    Conflict of Interest:
    None declared.
  • Published on:
    Adrenal crisis due to inhaled steroids not underestimated

    Dear Editor

    In response to comments by Pearce and Mabin on Professor Russell’s editorial[1] on our paper.[2]

    They doubt that our survey underestimated the true scale of the problem. I can inform them that this is not the case. Since our survey was completed we have been notified of a further 7 cases (5 children, 2 adults). All but one of the children had been taking fluticasone in similar dosages...

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    Conflict of Interest:
    None declared.