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Cataplexy in the Prader–Willi syndrome
  1. E S Tobias1,
  2. J L Tolmie1,
  3. J B P Stephenson2
  1. 1Duncan Guthrie Institute of Medical Genetics, Yorkhill Hospitals, Glasgow G3 8SJ, UK;
  2. 2Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK

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We report cataplexy, sudden atonic episodes provoked by emotion, in three patients with Prader–Willi syndrome (PWS) and suggest that cataplexy may be relatively common in this condition.

Detailed questioning of the mother of an 18 year old woman who had PWS elicited a history of recurrent attacks, apparently induced by laughter, with sudden loss of power in all the patient's limbs. If …

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