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Acute paediatrics
Immunoglobulin levels in methotrexate treated paediatric rheumatology patients

Abstract

Retrospective review of serum immunoglobulin levels in 78 methotrexate treated paediatric rheumatology patients showed that IgG, IgA, and IgM levels fell significantly by 26%, 21%, and 17% respectively while on methotrexate. Six patients with systemic disease showed a fall in IgG to below the normal range.

  • methotrexate
  • immunoglobulin
  • rheumatology
  • CRP, C reactive protein
  • ESR, erythrocyte sedimentation rate
  • Ig, immunoglobulin
  • JIA, juvenile idiopathic arthritis

https://doi.org/10.1136/adc.87.2.147

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