Article Text

Download PDFPDF

The meningococcus tamed?
Free
  1. A J Pollard,
  2. E R Moxon
  1. Oxford Vaccine Group, Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
  1. Correspondence to:
    Dr A J Pollard, Oxford Vaccine Group, Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK;
    andrew.pollard{at}paediatrics.ox.ac.uk

Abstract

Serogroup B Neisseria meningitidis is a frequent cause of invasive meningococcal disease, yet there are no effective vaccines suitable for routine immunisation. Limited efficacy has been shown with meningococcal outer membrane vacccines in children 4 years and older. Here we review the status of current research and consider new approaches to development of meningococcal serogroup B vaccines.

  • meningococcus
  • vaccine
  • meningitis
  • review
  • immunisation
  • Hib, Haemophilus influenzae type b
  • LPS, lipopolysaccharide
  • OMP, outer membrane protein
  • OMV, outer membrane vesicle

Statistics from Altmetric.com

Footnotes

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Atoms
    Harvey Marcovitch