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Clinical validation for oxacillin susceptibility testing of coagulase negative staphylococci
  1. N Cimolai1,
  2. J E Carter2
  1. 1Program of Microbiology, Virology, and Infection Control, Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia, Canada
  2. 2Division of Paediatric Nephrology, Department of Paediatrics, Children's and Women's Health Centre of British Columbia, Canada


Oxacillin susceptibility of coagulase negative staphylococci as assessed by conventional methods was confirmed by a modified Etest method, extended to detect heteroresistance. Verification of susceptibility was followed by successful treatment for six consecutive children with deep seated infections. Physicians' trust in such a validated method will contribute to the appropriate use of antibiotics.

  • staphylococcus
  • oxacillin
  • susceptibility testing
  • CNS, coagulase negative staphylococci
  • MIC, minimal inhibitory concentration
  • MRSA, methicillin resistant S aureus

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