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A16 month old boy with stage IV neuroblastoma and hypoalbuminaemia presented with a left sided haemorrhagic pleural effusion. He subsequently developed generalised oedema. You wonder if there was a role of albumin infusion in correcting hypoalbuminaemia and colloid osmotic pressure (COP), in order to treat the extravasation of fluid into tissue spaces.
Structured clinical question
In critically ill children with low serum albumin [patient group] does giving albumin infusion [intervention] improve COP and hence morbidity and mortality [outcome]?
Search strategy and outcome