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Kocher Debre Semelaigne syndrome: regression of pesudohypertrophy of muscles on thyroxine
  1. P Mehrotra,
  2. M Chandra,
  3. M K Mitra
  1. Department of Medicine, B/127 Nirala Nagar, Lucknow, PIN 226020, India
  1. Correspondence to
    Dr Mehrotra;

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Myopathy associated with hypothyroidism classically presents with proximal weakness, fatigue, exertional pain, slowed movement, diminished deep reflexes, stiffness, myalgia, myoedema, and less commonly, cramps. Rarely, muscle enlargement is also seen, and the term Kocher Debre Semelaigne syndrome (KDS syndrome) is used.1–3

We report the case of an 11 year old boy presenting with poor growth, mental retardation, diffuse exertional pain in …

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