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Lipid and glucose metabolism in HIV-1-infected children treated with protease inhibitors
  1. N M Vink1,
  2. A M C van Rossum1,
  3. N G Hartwig1,
  4. R de Groot1,
  5. S Geelen2
  1. 1Department of Pediatrics, University Hospital Rotterdam/ Sophia Children's Hospital Dr Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands rdegroot@alkg.azr.nl
  2. 2Department of Pediatrics, Wilhelmina Children's Hospital, Utrecht, The Netherlands

https://doi.org/10.1136/adc.86.1.67-a

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    The use of protease inhibitors (PIs) in patients with HIV-1/AIDS has been associated with peripheral lipodystrophy, hyperlipidemia and insulin resistance.1,2 However, all studies have been done in adults. The aim of this study was to evaluate the influence of highly active antiretroviral therapy (HAART) on serum levels of fasting triglyceride, total cholesterol, high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), free fatty acids (FFAs) and glucose in twenty HIV-1 infected children treated during a minimum period of 18 months with …

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