Editor,—The two publications on fertility preservation for children1 ,2 raise important issues but several issues need to be clarified.

Specifically, intracytoplasmic sperm injection (ICSI) is not a method to reverse male infertility in whatever circumstance. ICSI provides an effective solution to severe male infertility problem but offspring and partner issues need to be considered carefully.3-6 The suitability of pre-pubertal testicular tissue is questioned since technology surrounding cryopreservation and in vitro manipulation of prepubertal testicular tissue is stated as being “entirely experimental”. This is also true of adult testicular tissue which may similarly have immature germ cells.

The question of peripubertal boys and the use of rectal electrostimulation raises seriously important issues about the pain and psychological effect this procedure as a “first sexual experience” could have on the patients future sexual development and outlook.7 , …