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Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery
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Other responses

  • Published on:
    Reduction in Case Fatality Rate From Meningococcal Disease Is due to Genuine Teamwork
    • Simon Nadel, Paediatrician
    • Other Contributors:
      • Robert Booy, Parviz Habibi, Claudine De-Munter, Joseph Britto, Michael Levin

    Dear Editor

    We read with disappointment the response of Dr Petros and colleagues [1] to our article "Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery" [2]. It is unfortunate that there appears to be a misunderstanding of the message of our study which demonstrated a significant improvement in the mortality of children with meningococcal disease (MD) over a...

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    Conflict of Interest:
    None declared.
  • Published on:
    Genuine reduction in meningococcal deaths results from teamwork
    • Andy J Petros, Consultant Paediatric Intensivist
    • Other Contributors:
      • Dr Patricia Weir, Dr Michael Marsh, Dr Robert Yates, Dr Charles Ralston, Dr Pauline Cullen, Dr Paul Loan, Dr Paul Baines, Dr Mark Peters
    Dear Editor,

    As paediatric intensivists in Lead Centres accredited for paediatric intensive care (PIC) training and responsible for the care of approximately 7000 cases per year, we read with concern the report from St Mary's Hospital which reported improved outcome of Meningococcal Disease (MD) in 1997 compared to previous years[1].

    Their reported reduction in mortality must be seen in the context of an overall...

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    Conflict of Interest:
    None declared.
  • Published on:
    Re: Mortality in meningococcal disease: please report the figures accurately
    Editor,

    We thank Tibby and colleagues for their interest. We believe they and others would be interested in the accompanying figure.

    It compares yearly case fatality rates on all referrals to St Mary's PICU, regardless of whether they died before a mobile intensive care team arrived or while the team was assisting with resuscitation. The 29 ‘outside’ deaths are included (3 in 1992/3, 8 in 1994,10 in 1995, 3 in...

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    Conflict of Interest:
    None declared.
  • Published on:
    Inter-unit comparisons are flawed

    Dear Editor

    Mortality from meningococcal septic shock may be falling however it is difficult to be sure. Inter-unit comparisons of the sort precipitated by these articles and correspondence are inevitably distorted by confounding factors. These factors are not entirely removed by the use of mortality prediction models.

    Historically mortality data for meningococcal septicaemia from the UK Public Health...

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    Conflict of Interest:
    None declared.
  • Published on:
    Mortality in meningococcal disease: please report the figures accurately

    Dear Editor,

    We read with great interest the two recent articles on mortality in meningococcal disease.[1,2] Whilst we would agree with the message contained in both articles, namely that the mortality associated with this condition has decreased with time, we have serious concerns regarding the presentation of the data in the paper from the St Mary’s group.

    Booy and colleagues report a crude mortality of 2%...

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    Conflict of Interest:
    None declared.