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Symptomatic adrenal insufficiency during inhaled corticosteroid treatment
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  • Published on:
    Budesonide cases should not have been included

    Dear Editor,

    In this short report, Patel et al. presents a series of eight cases of ”symptomatic adrenal insufficiency during inhaled corticosteroid treatment” [1]. The paper highlights several interesting points. However, the determination of cases as “symptomatic”, the laboratory investigations performed to establish the diagnosis, and the selection of cases, can be seriously questioned.

    The a...

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    Conflict of Interest:
    None declared.
  • Published on:
    Systemic effects of inhlaed corticosteroids
    • Ranjan Suri, Respiratory Paediatricians
    • Other Contributors:
      • Sheila McKenzie

    Dear Editor

    In the short report by Patel et al,[1] the authors have described symptomatic adrenal insufficiency in eight children with mild to moderately severe asthma. What was the evidence that these children a) had asthma and b) merited treatment with inhaled corticosteroids? Inhaled corticosteroids are potent locally and are almost entirely transformed into inactive metabolites in the liver, so that their sy...

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    Conflict of Interest:
    None declared.