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Medicines for children and gentamicin toxicity
  1. LOUISE GRANT, Clinical Research Fellow
  1. PETER MACDONALD, Consultant Paediatrician
  1. Department of Paediatrics
  2. Southern General Hospital
  3. 1345 Govan Road
  4. Glasgow, UK
  5. louise@tadams.demon.co.uk
  6. Department of Paediatrics
  7. Southern General Hospital

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Editor,—Recently, we changed our gentamicin dosing regimen (2.5 mg/kg 18 hourly for preterms and 2.5 mg/kg 12 hourly for term infants) as it resulted in too many low peak blood levels. Levels were taken immediately before and 1 hour after the third dose. We changed to the regimen given in Medicines for Children (MFC)1 shown in table 1 .

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Table 1

Medicines for Children gentamicin dosing regimen

However, after …

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