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Short report
Idiopathic thrombocytopenic purpura and MMR vaccine
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  1. E Millera,
  2. P Waighta,
  3. C P Farringtonb,
  4. N Andrewsa,
  5. J Stowec,
  6. B Taylorc
  1. aImmunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, Colindale, London NW9 5EQ, UK, bDepartment of Statistics, The Open University, Milton Keynes MK7 6AA, UK, cRoyal Free Campus, Royal Free and University College Medical School, University College London, London NW3 2PF, UK
  1. Dr Millere.miller{at}phls.co.uk

Abstract

A CAUSAL ASSOCIATION BETWEEN MEASLES mumps–rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.

  • MMR
  • vaccine
  • idiopathic thrombocytopenia purpura

http://dx.doi.org/10.1136/adc.84.3.227

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